New Production Facility to Support the Manufacturing of Antibody-Drug Conjugate Medicines

New Production Facility to Support the Manufacturing of Antibody-Drug Conjugate Medicines

case_study1.jpg

Our customer, a leader in research-focused healthcare, required an expansion to their global production capacity of antibody-drug conjugates.
 

Key Results

  • Delivery of critical building services, piping systems and laboratory within a state of the art, greenfield facility
  • Complex integration of 3D models for a series of superskid modules
  • Successful expansion of production capabilities for biologic medicines across the customer’s global manufacturing network
     

Key Project Features

  • Greenfield production facility housing multiple antibodydrug conjugate production lines
  • Containment solution for the handling of highly active ingredients
  • Accelerated production schedule with skid and superskid approach
  • Increase in capacity of QC laboratories
     

Our Delivery

  • Full design and execution responsibility for the HVAC, piping design, laboratory and cleanrooms
  • Integrated and coordinated the 3D models to reduce construction schedule and facilitate installation
  • Innovative piping superskid for shaft services
  • Design and installation of a dedicated flexible multipurpose plant HVAC
  • Construction management (HVAC and piping)
  • Systems installation coordination, commissioning and handover
     

Value to Our Customer

  • Successful delivery of critical systems of the state of the art production facility
  • Intelligent 3D superskid design accelerated construction schedule and optimised the transfer between design and construction
  • Complex, modular HVAC solution permitted containment of highly active products
  • Innovative, lean laboratory process design allowed integration of the laboratory into the main production building
     

Key Applied Capabilities

  • Virtual Reality & 3D Solutions

    Our clients demand the latest and most effective digital tools in the delivery of our designs.

  • Facility Design

    We specialise in full facility design, integrating complex functional processes and laboratories throughout their entire life cycle.

  • Process Engineering

    We understand our clients’ operational and quality process needs, applying industry leading ideas from some of the best minds in our field.

  • Project Management & Controlling

    With our hands-on approach to project delivery strategies, our experienced project managers and their teams define and manage schedules, budgets and deliverables throughout the project lifecycle.

  • C&Q / QA / QP / MDR

    We support our clients in efficient and integrated commissioning and qualification, quality assurance, qualified person and medical device regulation activities.

  • Construction Management & HSE

    Our robust CM tools and skilled teams enable us to develop specific plans that deliver projects safely and to scope, time and budget.

  • Functional Safety Management

    We ensure our clients meet their regulatory safety obligations. We offer complete lifecycle functional management; bringing process and operational expertise together with the latest analysis tools.

  • Laboratories

    Intelligent environments and smart processes. Innovative integrated laboratory solutions delivered by our expert engineers, scientists and architects.

  • Building Services

    Flexible and high performance building services that are dynamic and responsive to the environmental needs of our clients.

Contact person

Other Case Studies

  • Hydro-Electric Power Station Electrical and Automation Systems

    Our client required a full update of the hydro-electric power station control system to the latest technology.

  • Greenfield Expansion for Solids Dosage Form Medicines

    Our customer, a leading pharmaceutical manufacturer required a significant increase in capacity of solid dosage form medicines.

  • New Production Facility to Support the Manufacturing Monoclonal Antibodies (mAbs)

    Our customer a leading pharmaceutical manufacturer needed to increase the production capacity of monoclonal antibodies as bio-pharmaceutical drug substance using mammalian cell cultures.

  • Expansion of R&D Building with New Pilot Plant for Continuous Drug Production

    Our customer, a leading pharmaceutical manufacturer required a new pilot plant for continuous drug production.

  • Modernisation of API production building

    Our customer, a leading pharmaceutical manufacturer needed a state-of -the-art manufacturing plant for their new blockbuster blood pressure product.